Estimation of Health Utility Values for Alopecia Areata

March 2024 in “ Quality of Life Research ”

Daniel Aggio, Caleb Dixon, Ernest H. Law, Rowena Randall, Thomas M Price, Andrew Lloyd

alopecia areata hair loss health state utility values HSUVs patient-reported outcomes

TLDR More severe hair loss in alopecia areata greatly impacts patients and caregivers.

The study aimed to estimate health state utility values (HSUVs) for alopecia areata (AA) using time trade-off interviews with 120 participants from the UK general population. Vignettes describing health states based on the severity of hair loss were developed using data from patient-reported outcomes, literature reviews, and interviews with patients, clinical experts, and caregivers. The results showed that more extensive hair loss had a more severe impact on patients, with HSUVs ranging from 0.502 for the most severe state to 0.919 for the mildest. The caregiver HSUV was 0.882, indicating a significant impact of AA on both patients and caregivers.

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