Anti-Inflammatory and Immunomodulating Properties of the Herbal Preparation Indicated for Prevention and Treatment of Alopecia

The study investigated the anti-inflammatory and immunomodulating properties of a herbal preparation for the prevention and treatment of alopecia, a chronic inflammatory disease often linked to autoimmune mechanisms. The preparation, containing Arctium lappa, Sophora japonica, Acorus calamus, Urtica dioica, and Humulus lupulus, was tested using various inflammatory models. Results showed that intragastric administration of the preparation reduced inflammation severity in animal models, decreased pulmonary edema, and reduced granulation tissue weight. It also activated macrophages, increased oxidative metabolite production, and enhanced cytokine secretion in human blood cells. The findings suggested that the herbal preparation had moderate potential for treating alopecia.