Exploring the Role of Hirudotherapy in Alopecia Areata: Immunological and Microcirculatory Perspectives

The document explores the potential of hirudotherapy, or leech therapy, as a complementary treatment for alopecia areata (AA), a chronic autoimmune disorder causing non-scarring hair loss. Traditional treatments like corticosteroids, topical immunotherapy, and JAK inhibitors often result in variable clinical responses and frequent relapses. The study suggests that hirudotherapy may offer benefits by improving microcirculation and modulating immune responses, although further research is needed to fully understand its efficacy and mechanisms in treating AA.