Hsa_circ_0002980 Prevents Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Liver Cancer Cells Through MicroRNA-1303/Cell Adhesion Molecule 2 Axis

December 2023 in “ Aging ”

Yu Wang, Zhenlin Li, Jun He, Wen-Xiang Chen, Yiming Li, Xiangmei Chen, Junjie Liang, Qiangfeng Yu, Jianyin Zhou

TLDR hsa_circ_0002980 can help stop liver cancer cells from growing and spreading.

The study investigates the role of hsa_circ_0002980 in liver cancer (LC) cells, revealing that its upregulation inhibits cell proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) by modulating the miR-1303/CADM2 axis. This suggests that targeting this axis could serve as a novel therapeutic approach for treating liver cancer.

View this study on pmc.ncbi.nlm.nih.gov →

Hsa_circ_0002980 Prevents Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Liver Cancer Cells Through MicroRNA-1303/Cell Adhesion Molecule 2 Axis

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