Generation of an Immortalized Human Hair Follicle Keratinocyte Cell Line Retaining Trichogenic Potential
July 2026
in “
Biochemical and Biophysical Research Communications
”
Research cited in this study
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Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
research High-Throughput Screening of 3D Co-Culture Hair Follicle Mimetic Tissue with Enhanced ECM for the Screening of Hair Growth Promoting Compounds
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research Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia
Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
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The method can test hair growth products using a lab-made hair-like structure that responds to known treatments.
research Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632
A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes
Reducing FOXA2 in skin cells lowers their ability to grow hair.
research Restoration of Hair-Inductive Activity of Cultured Human Follicular Keratinocytes by Co-Culturing with Dermal Papilla Cells
Growing hair cells with dermal cells can potentially treat hair loss.
research Establishment of Keratinocyte Cell Lines from Human Hair Follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research Establishment and Characterization of Five Immortalized Human Scalp Dermal Papilla Cell Lines
Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.
research A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles
Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
research Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells
Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
research Review of Hair Follicle Dermal Cells
Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
research Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles
Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
research Isolation and Short-Term Culture of Primary Keratinocytes, Hair Follicle Populations, and Dermal Cells from Newborn Mice and Keratinocytes from Adult Mice for In Vitro Analysis and Grafting to Immunodeficient Mice
research Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray
Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.
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