An Improved Synthesis of Finasteride from 4-Androsten-3,17-Dione
December 2010
in “
Asian Journal of Research in Chemistry
”
TLDR The new method makes finasteride cheaper and easier to produce.
The document described an improved synthesis method for finasteride, a drug used to treat benign prostatic hyperplasia. The synthesis was achieved through a seven-step process starting from 4-androsten-3,17-dione, resulting in an overall yield of 20.01%. The improvements made the process less expensive and more commercially viable compared to previous methods reported in the literature.