TLDR Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
The study concluded that inactivation of the Vitamin D Receptor (VDR) in mice increased their susceptibility to UV-induced skin tumorigenesis. VDR−/− mice developed skin tumors more rapidly and frequently than wildtype controls, showing compromised DNA repair, defective UV-induced growth arrest and apoptosis, and reduced epidermal thickening in response to UV exposure. These findings highlighted the critical protective role of VDR in preventing UV-induced skin damage and tumor formation, independent of its ligand, 1,25(OH)2D3. The study involved various groups of mice with sample sizes ranging from 6 to 23 per group.
Hair loss theory suggests imbalance between VitaminDReceptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.
VitaminD may counteract DHT and help with hair growth, as seen in mice and human hair cultures. Some users discuss using VitaminD, magnesium, and other supplements for hair health, while others humorously note the success in mice.
VitaminD supplementation may have led to slight hair regrowth and density improvement. Other treatments discussed include finasteride, minoxidil, and maintaining optimal vitaminD levels.
VitaminD tests like D2, D3, and 25-hydroxyvitamin D are discussed before starting hair treatment. VitaminD can be obtained from food, but overdose has side effects.
The conversation discusses recommendations for Vitamin D3 supplements for hair health. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
A user found out they are vitaminD deficient and was prescribed high-dose vitaminD supplements, asking if others had similar experiences and if it improved their hair. Some shared improved mood and testosterone levels after treatment, while another combined vitaminD supplements with finasteride due to family history of baldness.
