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GlossarySkin Tumors

abnormal growths of skin cells, benign or malignant

Skin tumors, also known as skin neoplasms or cutaneous tumors, are abnormal growths of skin cells that can be benign (non-cancerous) or malignant (cancerous). These growths can arise from various types of skin cells, including melanocytes, keratinocytes, and other cell types, and can manifest as moles, warts, or more serious conditions like melanoma and basal cell carcinoma. Early detection and diagnosis are crucial for effective treatment and management.

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Research

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research Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis

148 citations , May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

research CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice

141 citations , May 2007 in “Cancer Research”

CD34 is crucial for skin tumor development in mice.

research Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

136 citations , March 1998 in “Oncogene”

Overexpression of E2F1 can lead to skin tumors and disrupt hair growth.

research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation

49 citations , October 2009 in “Cancer research”

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

research Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8‐expressing transgenic mice

49 citations , August 2004 in “The FASEB Journal”

Mice with human skin protein K8 had more skin problems and cancer.

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community Topical tretinoin increases minoxidil absorption by 3x. Thoughts?

in Minoxidil 36 upvotes 7 years ago

Topical tretinoin can increase the absorption of minoxidil by three times, which may enhance its effectiveness for hair loss treatment. Tretinoin causes increased skin turnover, making the skin more permeable and potentially improving minoxidil's efficacy.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 1 year ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Holy shit. Verteporfin may actually be the cure

in Research/Science 1019 upvotes 2 years ago

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

community Excessive hair growth from Minoxidil

in Is this regrowth? 434 upvotes 1 year ago

Minoxidil foam and oral finasteride resulted in significant hair regrowth, especially on the hairline, with no side effects from finasteride. The user applied Rogaine 5% for minoxidil.

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