International Consensus Guidelines on the Safe and Evidence-Based Practice of Mesotherapy: A Multidisciplinary Statement

The document provides international consensus guidelines for the safe and evidence-based practice of mesotherapy, developed by experts from 16 countries. Mesotherapy involves microinjections for localized treatment, minimizing systemic effects, and is used in various medical fields, including dermatology for conditions like alopecia. The guidelines emphasize standardized practices, such as aseptic techniques and appropriate needle use, to ensure safety and efficacy. While mesotherapy shows promise in managing musculoskeletal pain, sports injuries, and chronic venous disease, further high-quality research is needed to confirm its efficacy and safety, particularly in experimental applications. The guidelines also stress the importance of informed consent, ethical practice, and ongoing research to address evidence gaps and ensure patient safety.