Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects

The document reviewed mesotherapy, a technique involving intradermal drug injections, highlighting its historical development, technique, and potential benefits for localized pain management and conditions like alopecia. It noted that mesotherapy could provide significant pain relief with reduced medication and fewer adverse events compared to systemic treatments, due to both pharmacological and mechanical effects. Despite its widespread use, there was a lack of randomized studies on injection depths, and the efficacy varied with different drugs and conditions. The document emphasized the need for individualized treatment plans, safety concerns, and qualified professionals to perform the procedure. It also discussed the economic benefits and future prospects of mesotherapy, suggesting it could become a method to study drug-skin interactions, with further research needed to understand its therapeutic value.