Intravital Imaging of Host–Parasite Interactions in Skin and Adipose Tissues

The document reviewed the use of intravital microscopy (IVM) to study host-parasite interactions in skin and adipose tissues, providing insights into the behavior and transmission of parasites like Plasmodium, Trypanosoma, and Leishmania. IVM allowed visualization of these interactions at cellular levels, revealing the skin as a key entry point and reservoir for parasites, while adipose tissue played a role in parasite biology. The study of Plasmodium spp. highlighted sporozoite migration and behavior, with implications for malaria research. IVM also showed the skin as a reservoir for Trypanosoma brucei and explored immune responses in Leishmania infections. The document emphasized the potential of IVM in advancing the understanding of parasite dynamics and host immune responses, suggesting future research directions using humanized models and technological advancements.