Essential Resources and Best Practices for Laboratory Mouse Research

This guide emphasizes the importance of laboratory mice in research due to their genetic similarity to humans and practical advantages as model organisms. It highlights specialized mouse strains like BXD recombinant inbred and Diversity Outbred mice for studying complex genetic traits and diseases. Proper mouse husbandry, including housing and diet, is crucial for reliable outcomes. Ethical considerations are addressed through the 3Rs principle—Replacement, Reduction, and Refinement—to ensure humane treatment. The guide serves as an introductory resource for researchers to effectively use mouse models in advancing scientific discovery and translating findings to human health applications.