Leydig Cell Ovarian Tumor: A Rare Cause of Hyperandrogenism

This document presents a case study of a postmenopausal woman with androgenic alopecia and elevated testosterone levels, attributed to a rare Leydig cell ovarian tumor. A CT scan revealed an enlarged right ovary with a high-density nodule and an incidental adrenal nodule. The patient underwent bilateral salpingo-oophorectomy, which confirmed a benign Leydig cell tumor in the right ovary and Leydig cell hyperplasia in the left. Post-surgery, her testosterone levels improved significantly. The case underscores the diagnostic challenges of hyperandrogenism in postmenopausal women, often linked to ovarian or adrenal origins, and highlights that bilateral salpingo-oophorectomy is an effective treatment for Leydig cell tumors.