Lichen Planus Pigmentosus in North Africa: A Series of 17 Cases
November 2019
in “
Dermatology - Open Journal
”
TLDR Lichen planus pigmentosus is hard to treat and may be more common in North Africa than previously thought.
The study reported on 17 cases of lichen planus pigmentosus (LPPig) in Moroccan patients, highlighting its presence in North Africa, a region where it was previously underreported. The study included 1 man and 16 women, with a mean age of 57.4 years. The condition predominantly affected the face, particularly the perioral area and forehead, and was associated with frontal fibrosing alopecia in 41% of cases. Some patients also had thyroiditis or diabetes mellitus. Histological analysis confirmed pigment incontinence and basal vacuolization. Treatment with tranexamic acid and topical hydroquinone showed limited success, with only 4 patients achieving complete resolution. The study concluded that LPPig is a challenging pigmentary disorder to treat, and its prevalence in North Africa may be underestimated.