Lichen Planus Pigmentosus: A Clinico-Pathological Study in a Caucasian Population from North Africa

    June 2023 in “ International Journal of Dermatology ”
    Massara Baklouti, Khadija Sellami, Mariem Rekik, Slim Charfi, Tahya Sellami, H. Turki
    TLDR Lichen planus pigmentosus mainly affects middle-aged women with darker skin, is underreported, and is hard to treat.
    This study investigates lichen planus pigmentosus (LPP) in a Caucasian population from southeastern Tunisia, involving 41 patients over a 6-year period. The study found that LPP predominantly affects middle-aged women with darker skin phototypes, presenting as brown-gray to purplish-gray macules, primarily on the face and neck. The most common pigmentation pattern was blotchy, and pruritus was present in 53% of cases. Dermoscopic analysis revealed brown to gray-blue perifollicular hyperpigmentation as a common feature. LPP was associated with other lichen planus variants and conditions like dysthyroidism and hepatitis B. The study highlights that LPP, though rare in Caucasians, is underreported and has a significant social impact due to its aesthetic effects. Treatment is challenging, with pigmentation often resistant to therapy, emphasizing the importance of avoiding trigger factors and identifying comorbidities.
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