Low-Sulfur Hair Syndrome Associated with UVB Photosensitivity and Testicular Failure

The document described a case of a 16-year-old male with a syndrome characterized by growth and mental retardation, hair shaft abnormalities, neurosensory hearing loss, contractures of the fifth fingers, UVB photosensitivity, small testicular size, and elevated follicle-stimulating hormone levels. The patient exhibited low-sulfur hair content and a unique pattern of birefringent bands in hair under polarization microscopy, typical of low-sulfur hair syndrome. Notably, UVB photosensitivity and testicular failure were newly identified components of this syndrome at the time.