Association of Severity of Menstrual Dysfunction With Cardiometabolic Risk Markers Among Women With Polycystic Ovary Syndrome

    May 2024 in “ Acta Obstetricia Et Gynecologica Scandinavica ”
    LI Xue-lan, Jie Yang, Christophe Blockeel, Min Lin, Xiaoyan Tian, Haocun Wu, Yaqi Cao, Ling Deng, Xian‐Li Zhou, Jinying Xie, Guohui Fan, Xin Chen
    TLDR Severe menstrual issues in PCOS women signal higher risk for heart and metabolic problems.
    This study involving 154 women with polycystic ovary syndrome (PCOS) found that those with amenorrhea had a significantly higher prevalence of insulin resistance, prediabetes, and dyslipidemia compared to women with oligomenorrhea or eumenorrhea. The severity of menstrual dysfunction was associated with increased cardiometabolic risks, suggesting it can serve as a marker for identifying PCOS women at higher risk for these conditions. The study emphasizes the importance of menstrual regularity as an indicator of health and suggests early intervention strategies to restore regular menstruation and reduce cardiometabolic risks. Limitations include its retrospective design and reliance on self-reported menstrual regularity.
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