Microneedling Combined With 5% Minoxidil for Female Pattern Hair Loss: A Retrospective Study on Efficacy and Safety

    January 2026 in “ Dermatologic Therapy
    Lulu Yang, Wei Cui, Zhongfa Lu
    TLDR Combining microneedling with 5% minoxidil is a safe and effective treatment for female pattern hair loss, promoting significant hair regrowth.
    This retrospective study evaluated the efficacy and safety of combining microneedling with 5% minoxidil solution in 40 female patients with androgenetic alopecia. Over 12 weeks, patients received weekly treatments, resulting in a 90% overall efficacy rate, with 13 showing significant improvement, 17 moderate improvement, 6 mild improvement, and 4 no response. The average increase in hair density was 17.98 ± 8.3 hairs/cm². Treatment efficacy was positively correlated with disease severity but not with patient age. No serious adverse reactions were reported, indicating that this combination is a safe and effective treatment for female pattern hair loss, offering significant hair regrowth with minimal side effects.
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