MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells

May 2023 in “ Proceedings of the National Academy of Sciences ”

Jingjing Wang, Yuheng Fu, Wenmao Huang, Ritusree Biswas, Avinanda Banerjee, Joshua A. Broussard, Zhihai Zhao, Dongmei Wang, Glen A. Bjerke, S. Raghavan, Jie Yan, Kathleen J. Green, Rui Yi

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research Foxc1 Reinforces Quiescence in Self-Renewing Hair Follicle Stem Cells

142 citations , February 2016 in “Science”

Foxc1 helps keep hair follicle stem cells inactive, preventing hair loss.

research Intravital Imaging of Hair Follicle Regeneration in the Mouse

56 citations , June 2015 in “Nature Protocols”

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

research Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4

75 citations , March 2014 in “Journal of Investigative Dermatology”

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors

66 citations , December 2013 in “Nature Cell Biology”

Inactive hair follicle stem cells help prevent skin cancer.

research Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration

305 citations , June 2012 in “Nature”

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.