MiR-200c-3p as a Novel Genetic Marker and Therapeutic Tool for Alopecia Areata

March 2024 in “ Skin Research and Technology ”

Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghadah Alhetheli

miR-200c-3p alopecia areata PLCG1 RPS6KP1 EGFR tyrosine kinases AA

TLDR miR-200c-3p could help diagnose and treat alopecia areata.

The study identifies miR-200c-3p as a novel genetic marker and potential therapeutic tool for alopecia areata (AA). Researchers found that miR-200c-3p influences the PLCG1 and RPS6KP1 genes, which regulate the EGFR tyrosine kinases resistance pathway, showing a significant increase in activity. These findings suggest that miR-200c-3p could play a theranostic role in the treatment and diagnosis of AA.

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