Unraveling the Impact of miRNAs on Gouty Arthritis: Diagnostic Significance and Therapeutic Opportunities

    November 2024 in “ Naunyn-Schmiedeberg s Archives of Pharmacology ”
    Sherif S. Abdel Mageed, Hanan Elimam, Ahmed E. Elesawy, Ahmed I. Abulsoud, Ahmed Amr Raouf, Manar Mohammed El Tabaa, Osama A. Mohammed, Mohamed Bakr Zaki, Mai A. Abd‐Elmawla, Walaa A. El‐Dakroury, Safwat A. Mangoura, Mahmoud A. Elrebehy, Mohammed S. Elballal, Aya A. Mohamed, Alaa Ashraf, Mustafa Ahmed Abdel‐Reheim, Ali M. S. Eleragi, Hussein Abdellatif, Ahmed S. Doghish
    TLDR miRNAs could help diagnose and treat gouty arthritis.
    This review explores the role of microRNAs (miRNAs) in gouty arthritis, an inflammatory illness caused by uric acid imbalance. miRNAs, which regulate protein synthesis, are increasingly recognized for their involvement in inflammatory diseases like gouty arthritis. They may affect disease progression by modulating immune function and inflammatory responses. The review highlights the potential of miRNAs as diagnostic and prognostic tools, as well as therapeutic targets for gouty arthritis.
    Discuss this study in the Community →