Multifunctional applications of natural polysaccharide starch and cellulose: An update on recent advances

    December 2021 in “ Biomedicine & Pharmacotherapy ”
    V. Gopinath, S. Manjunath Kamath, S. Priyadarshini, Zamri Chik, Abdullah A. Alarfaj, Abdurahman Hajinur Hirad
    TLDR Starch and cellulose are promising for drug delivery and tissue engineering due to their biocompatibility.
    This review discussed the advancements and potential of natural polymers, specifically cellulose and starch, in drug delivery and tissue engineering applications. It highlighted the challenges related to solubility and functionalization due to their complex structures. The review covered the use of these biopolymers in creating hydrogels, films, and composites for treating bone infections, microbial infections, and cancers. It also touched on the promising yet challenging application of metal-drug-based polymeric systems in cancer therapeutics. The high biocompatibility of starch and cellulose made them valuable in biomedical and pharmaceutical fields, with a focus on developing biopolymer-based vehicles for drug, gene, and protein delivery.
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