Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways

The review highlighted myricetin, a polyhydroxy flavonol found in various plants, as a promising anticancer agent due to its antioxidant, anti-inflammatory, and hepato-protective properties. It demonstrated potential in cancer prevention by modulating angiogenesis, inflammation, cell cycle arrest, and apoptosis, and inhibiting inflammatory markers like iNOS and Cox-2. Myricetin also enhanced the efficacy of existing anticancer drugs by modulating cell signaling molecules. The review emphasized the need for further research on myricetin's safety, effective dosing, and clinical trial implications, as well as the development of nanoformulations to improve its bioavailability and targeted delivery.