Nanoformulation of Medicinal Plant Compounds for Improved Drug Delivery and Pharmacological Activity

This review discusses the use of nanotechnology to improve the drug delivery and pharmacological activity of bioactive phytochemicals from medicinal plants, which often face challenges like poor solubility and low bioavailability. Nanoformulation techniques, such as liposomes, polymeric nanoparticles, and nanoemulsions, significantly enhance the solubility, stability, and bioavailability of these compounds, allowing for targeted and controlled drug delivery. These methods have shown increased therapeutic efficiency in models of cancer, neurological diseases, inflammatory diseases, and microbial infections. The review highlights the potential of nano-phytomedicine, emphasizing the need for further research on formulation optimization, safety, and clinical translation to integrate these advancements into modern pharmaceuticals.