TLDR Nanotechnology can improve treatments for skin discoloration.
The review discusses the potential of nanotechnology-based approaches for managing hyperpigmentation disorders, particularly melasma, by using various nanocarriers such as lipid nanoparticles, gold nanoparticles, and polymer-based systems. These nanocarriers enhance the delivery, stability, and efficacy of anti-hyperpigmenting agents, improving skin penetration and targeting, which leads to more effective treatment outcomes. The document emphasizes the advantages of these advanced formulations in increasing drug concentration in deeper skin layers and reducing adverse effects, suggesting that nanotechnology could provide more effective and targeted therapies for hyperpigmentation disorders. However, further research and clinical trials are necessary to fully understand their potential and safety.
10 citations
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July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
68 citations
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January 2020 in “International Journal of Pharmaceutics” Vitamin C-based nanovesicles effectively treat acne.
40 citations
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July 2018 in “European Journal of Pharmaceutical Sciences” Melatonin vitamin C-based nanovesicles improved hair growth and reduced hair loss in androgenic alopecia patients.
15 citations
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December 2016 in “Advanced Pharmaceutical Bulletin” The new cream with N-acetyl glucosamine didn't change skin color after 8 weeks.
91 citations
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August 2015 in “Anais Brasileiros De Dermatologia” Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
222 citations
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January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems” Ethosomes can safely and effectively deliver various drugs deep into the skin.
130 citations
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August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
20 citations
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January 2022 in “REVIEWS ON ADVANCED MATERIALS SCIENCE” Nanoparticles can make cosmetics more effective but have challenges like cost and safety.
January 2025 in “Pharmaceuticals” Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.
February 2024 in “International Journal For Multidisciplinary Research” Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.
222 citations
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January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems” Ethosomes can safely and effectively deliver various drugs deep into the skin.