Advances in Nanotechnology-Based Topical Delivery Systems for Skincare Applications

January 2026 in “ Pharmaceutics ”

Yan Zheng, Shuqi Zhang, Guyuan Wu, Yunxiang Kang, Cong Fu, Zihan Wang, G.L. Wang, Lu Tang, Wei Wang

TLDR Nanotechnology in skincare improves ingredient stability, skin penetration, and controlled release for better cosmetic solutions.

This review discusses the advancements in nanotechnology-based topical delivery systems for skincare, highlighting their ability to enhance skincare formulations by stabilizing and protecting ingredients, improving skin penetration, and enabling controlled release. It covers various nanocarrier platforms, such as vesicular, lipid-based, emulsion-based, polymeric, inorganic nanoparticles, and inclusion complexes, and their application in addressing skin disorders. The review emphasizes the potential of these technologies to provide precise and effective cosmetic solutions, reflecting emerging trends and future directions in cosmetology.

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Advances in Nanotechnology-Based Topical Delivery Systems for Skincare Applications

Research cited in this study

research Preparation and In Vitro Evaluation of Protective Effects of Quercetin-Loaded Solid Lipid Nanoparticles on Human Hair Against UV-B Radiation

research Enhancing Hair Regeneration: Recent Progress in Tailoring Nano-Structured Lipid Carriers Through Surface Modification Strategies

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research Common Causes of Hair Loss

research Nanocarriers as Active Ingredients Enhancers in the Cosmetic Industry—The European and North America Regulation Challenges

research Nanomaterials in Hair Care and Treatment

research Current Advances of Nanocarrier Technology-Based Active Cosmetic Ingredients for Beauty Applications

research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications

research Cosm-Nutraceutical Nanovesicles for Acne Treatment: Physicochemical Characterization and Exploratory Clinical Experimentation

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