Nonsurgical Facial Aesthetic Procedures

January 2023

Marina A. Carro, Emre Tokgöz

TLDR Nonsurgical facial procedures are popular because they improve appearance with minimal risks and quick recovery.

Nonsurgical facial rejuvenation gained popularity due to advancements that improved results with minimal side effects and short recovery times, reducing the risks associated with invasive surgery. Various treatments targeted the hairline, facial contour, wrinkles, and volume replacement, typically as quick outpatient procedures. The document discussed available nonsurgical modalities, including hairline augmentation, skin treatments, injectable fillers, and neuromodulators.

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Research cited in this study

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research Comparing the Frequency of Isotretinoin-Induced Hair Loss at <0.5 mg/kg/d Versus ≥0.5 mg/kg/d Dosing in Acne Patients: A Systematic Review

6 citations , February 2022 in “JAAD International”

Higher doses of isotretinoin may lead to more hair loss.

research Female Pattern Hair Loss

January 2022 in “Springer eBooks”

research Hair Transplantation: Basic Overview

30 citations , April 2021 in “Journal of The American Academy of Dermatology”

Hair transplantation can effectively restore hair in balding areas.

research Male and Female Pattern Hair Loss: Treatable and Worth Treating

11 citations , March 2021 in “Cleveland Clinic Journal of Medicine”

Treating hair loss in both men and women is effective and improves quality of life.

research Non-Surgical Modalities of Facial Rejuvenation and Aesthetics

3 citations , January 2021

Non-surgical treatments like thread lifts, PRP therapy, HIFU, and radiofrequency effectively rejuvenate and tighten facial skin.

research Minoxidil And Its Use In Hair Disorders: A Review

117 citations , August 2019 in “Drug Design Development and Therapy”

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

research Platelet-Rich Plasma and Stem Cells for Hair Growth: A Review of the Literature

12 citations , May 2019 in “Aesthetic Surgery Journal”

Platelet-Rich Plasma and stem cell therapy can increase hair count and density, but the best method for preparation and treatment still needs to be determined.

research Correction of Tear Trough Deformity Using Autologous Fibroblast Combined with Keratin: New Soft Tissue Filler

12 citations , November 2018 in “Aesthetic plastic surgery”

The new filler effectively and safely improves tear trough deformity long-term.

research Female Pattern Hair Loss

11 citations , July 2018 in “AJGP”

Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.

research Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue

36 citations , February 2018 in “British Journal of Dermatology”

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

Nail Involvement in Alopecia Areata: A Questionnaire-Based Survey on Clinical Signs, Impact on Quality of Life, and Review of the Literature

research Nail Involvement in Alopecia Areata: A Questionnaire-Based Survey on Clinical Signs, Impact on Quality of Life, and Review of the Literature

19 citations , January 2018

Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.

research Evaluation of Hair Density in Different Ethnicities in a Healthy American Population Using Quantitative Trichoscopic Analysis

31 citations , December 2017 in “Skin Appendage Disorders”

Caucasians have the highest hair density, followed by Hispanics, with the lowest in individuals of African descent.

research Hair Pull Test: Evidence-Based Update and Revision of Guidelines

36 citations , December 2016 in “Journal of The American Academy of Dermatology”

The normal range for the hair pull test is 2 hairs or fewer, and washing or brushing hair before the test does not affect the results.

research Androgenetic Alopecia: An Update Of Treatment Options

110 citations , August 2016 in “Drugs”

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

research Complications Caused by Injection of Dermal Filler in Danish Patients

2 citations , June 2016 in “European Journal of Plastic Surgery”

Dermal filler injections can cause complications like swelling and infections, often appearing years later.

research Interventions for Female Pattern Hair Loss

21 citations , May 2016 in “The Cochrane library”

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

343 citations , October 2015 in “Endocrine Practice”

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

research Classification and Scoring of Androgenetic Alopecia (Male and Female Pattern)

January 2015

The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle

research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle

149 citations , July 2014 in “Cold Spring Harbor Perspectives in Medicine”

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

research Phototrichogram Analysis of Normal Scalp Hair Characteristics with Aging

16 citations , November 2013 in “European Journal of Dermatology”

Hair gets thinner and grayer with age, and density decreases more in men on top and in women on top and back.

The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride

research The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride

66 citations , June 2013 in “Journal of Dermatological Treatment”

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations , January 2013 in “International Journal of Trichology”

research Hair and Scalp Dermatoscopy

245 citations , March 2012 in “Journal of The American Academy of Dermatology”

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia

research A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia

81 citations , August 2011 in “Journal of The American Academy of Dermatology”

Latanoprost 0.1% may effectively treat hair loss.

research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia

152 citations , October 2010 in “Archives of Dermatology”

Finasteride helps hair growth but may cause sexual side effects.

research Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome

54 citations , February 2010 in “British Journal of Dermatology”

Hair loss in women may have causes other than hormones.

research Hair Evaluation Methods: Merits and Demerits

91 citations , January 2009 in “International Journal of Trichology”

Different hair evaluation methods have their own pros and cons, and using multiple methods together is best for accurate hair loss diagnosis and tracking.

research Hairline Design in Hair Replacement Surgery

25 citations , November 2008 in “Facial Plastic Surgery”

Dr. Michael Beehner recommends a personalized, careful approach to hairline design in hair replacement surgery for a natural look.

The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

215 citations , November 2006 in “Journal of The American Academy of Dermatology”

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Treatment of Female Pattern Hair Loss With Oral Antiandrogens

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

research Hair Loss in Psychopharmacology

63 citations , March 2000 in “Annals of clinical psychiatry”

Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.

research The Midline Part: An Important Physical Clue to the Clinical Diagnosis of Androgenetic Alopecia in Women

90 citations , January 1999 in “Journal of The American Academy of Dermatology”

"Christmas tree" pattern helps diagnose female hair loss.

Nonsurgical Facial Aesthetic Procedures

Research cited in this study

research Comparing the Frequency of Isotretinoin-Induced Hair Loss at <0.5 mg/kg/d Versus ≥0.5 mg/kg/d Dosing in Acne Patients: A Systematic Review

research Female Pattern Hair Loss

research Hair Transplantation: Basic Overview

research Male and Female Pattern Hair Loss: Treatable and Worth Treating

research Non-Surgical Modalities of Facial Rejuvenation and Aesthetics

research Minoxidil And Its Use In Hair Disorders: A Review

research Platelet-Rich Plasma and Stem Cells for Hair Growth: A Review of the Literature

research Correction of Tear Trough Deformity Using Autologous Fibroblast Combined with Keratin: New Soft Tissue Filler

research Female Pattern Hair Loss

research Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue

research Nail Involvement in Alopecia Areata: A Questionnaire-Based Survey on Clinical Signs, Impact on Quality of Life, and Review of the Literature

research Evaluation of Hair Density in Different Ethnicities in a Healthy American Population Using Quantitative Trichoscopic Analysis

research Hair Pull Test: Evidence-Based Update and Revision of Guidelines

research Androgenetic Alopecia: An Update Of Treatment Options

research Complications Caused by Injection of Dermal Filler in Danish Patients

research Interventions for Female Pattern Hair Loss

research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

research Classification and Scoring of Androgenetic Alopecia (Male and Female Pattern)

research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle

research Phototrichogram Analysis of Normal Scalp Hair Characteristics with Aging

research The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

research Hair and Scalp Dermatoscopy

research A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia

research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia

research Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome

research Hair Evaluation Methods: Merits and Demerits

research Hairline Design in Hair Replacement Surgery

research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

research Treatment of Female Pattern Hair Loss With Oral Antiandrogens

research Evaluation and Treatment of Male and Female Pattern Hair Loss

research Hair Loss in Women with Hyperandrogenism: Four Cases Responding to Finasteride

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research Hair Loss in Psychopharmacology

research The Midline Part: An Important Physical Clue to the Clinical Diagnosis of Androgenetic Alopecia in Women