Evaluation of a Novel Dermal Cooling System for the Treatment of Benign Pigmented Lesions in Asians

The study evaluated a novel dermal cooling system (DCS) for treating benign pigmented lesions in 81 Asian patients, involving 305 sessions and 1716 lesion sites. The DCS, which provided localized cooling less intense than cryotherapy, was administered up to 10 times at 4-week intervals. Results showed that 76.5% and 58.6% of treatment sites exhibited obvious to marked improvement at 2 months posttreatment, with sustained effects at 6 and 12 months. Minor adverse events like erythema and edema were common, while postinflammatory hyperpigmentation occurred in only 2.2% of treated sites. The study concluded that the DCS is an effective, safe, and well-tolerated treatment for benign pigmented lesions in Asians.