A Novel Approach for Follicular Delivery of Minoxidil for Treatment of Alopecia
July 2017
in “
Journal of Drug Delivery Science and Technology
”
TLDR Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
In 2017, researchers Maitra, Goyal, and Rath developed a new method for delivering minoxidil, a common alopecia treatment, directly to hair follicles. They created a minoxidil-loaded microemulsion, characterized by a globule size of 41.0nm, a zeta potential of +28.22mV, and a transmittance of 98.1%. The microemulsion showed an in-vitro release of 68.5% after 24 hours and 67.5% drug retention inside the hair shaft in ex-vivo studies. The formulation significantly altered the follicular response in a 5-Fluorouracil induced alopecia model. The study concluded that this novel approach could be a promising treatment for alopecia and other follicular diseases.
