Formulation and Evaluation of Minoxidil Loaded Submicron Emulsion Based Topical Gel for Treatment of Alopecia

    December 2023 in “ Azerbaijan Pharmaceutical and Pharmacotherapy J ”
    Jasjeet Kaur Narang, Ramandeep Singh Narang, . Mehak
    Image of study
    TLDR The minoxidil gel could be a better treatment for hair loss than traditional forms.
    The study formulated a minoxidil-loaded submicron emulsion-based topical gel for alopecia treatment. The emulsion was prepared using Clove oil, Tween 20, and Transcutol P, with the optimized formulation (M5) showing a pH of 5.4, in vitro release of 95.08%, ex vivo permeation of 79.36%, and a particle size of 181.3nm. The M5 formulation was then converted into a gel using Carbopol 934. The gel showed anti-oxidant potential and remained stable for three months. The study concluded that this minoxidil-loaded submicron emulsion-based topical gel could be a beneficial nano-approach for treating alopecia compared to traditional topical dosage forms.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community RU and cetosomal minoxidil topical

      in Minoxidil  1 upvotes 2 days ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community Chest pain on Oral minoxidil (18M)

      in Minoxidil  38 upvotes 4 days ago
      An 18-year-old experienced chest pain, headaches, and vomiting after taking oral minoxidil for hair loss. They reduced the dosage, felt better, but experienced sharp chest pain again after increasing it, and are advised to stop the medication and see a doctor.

      community Extreme shedding after ~1 year on 5% topical minoxidil — normal or problem?

      in Minoxidil  3 upvotes 1 week ago
      A 17-year-old using 5% topical minoxidil experienced significant hair shedding after a year, possibly due to a "synchronization shed" and deficiencies in vitamin D and iron. Recommendations include continuing minoxidil, optimizing vitamin D and iron levels, and reducing tretinoin use if scalp irritation occurs.

      community Counterfeit Kirkland minoxidil warning

      in Minoxidil  167 upvotes 1 week ago
      Counterfeit Kirkland minoxidil is being sold online, leading to ineffective hair loss treatment. Users are advised to purchase from reputable sources like Costco to avoid fake products.

      community Do you think oral minoxidil will become the standard for hair loss in 2026?

      in Minoxidil  142 upvotes 2 weeks ago
      Oral minoxidil is considered more convenient and effective for some users, with positive results reported, but concerns about side effects and availability persist. Finasteride remains a standard treatment, while some users explore combinations with other treatments like dutasteride and laser devices.

    Similar Research

    5 / 1000+ results