Unlocking The Potential Of Oleanolic Acid: Integrating Pharmacological Insights And Advancements In Delivery Systems

Oleanolic acid (OA) is a triterpenoid with significant pharmacological effects, including antidiabetic, anti-inflammatory, immune-enhancing, gastroprotective, hepatoprotective, antitumor, and antiviral properties. However, its therapeutic potential is limited by challenges such as poor aqueous solubility and restricted bioavailability. To address these issues, the document explores various advancements in drug delivery systems aimed at enhancing OA's biopharmaceutical properties and overall efficacy in different therapeutic contexts. Novel formulation strategies are essential to fully realize OA's therapeutic benefits.