Comparison of Resumption of Ovulation After Cessation of Oral Contraceptives and Medroxyprogesterone Acetate in Women With Polycystic Ovary Syndrome

    February 2024 in “ Gynecological Endocrinology
    Soo Jin Han, Hoon Kim, Seung‐Yup Ku, Chang Suk Suh
    TLDR Medroxyprogesterone acetate is as effective as oral contraceptives for resuming ovulation in women with PCOS.
    The study compares the resumption of ovulation in women with polycystic ovary syndrome (PCOS) after stopping oral contraceptives (OCPs) and medroxyprogesterone acetate (MPA). It concludes that MPA users have a similar likelihood of ovulation resumption as OCP users once the medication is ceased. Therefore, cyclic MPA can serve as a viable alternative for women who cannot take OCPs or choose not to use them.
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