Efficacy of Oxygen-Enriched Platelet-Rich Plasma Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Retrospective Study

This retrospective study evaluated the efficacy and safety of oxygen-enriched platelet-rich plasma (PRP) combined with 5% minoxidil compared to minoxidil monotherapy in treating androgenetic alopecia (AGA) in 72 patients. The combination treatment involved 5 PRP injection sessions at two-week intervals alongside daily topical minoxidil, while the control group used minoxidil alone. Results indicated that the combination group experienced significantly greater improvements in hair density, hair diameter, and follicular density, with higher satisfaction scores reported by both patients and physicians. No significant differences were found in terminal hair ratio or mean number of hairs per follicular unit. Adverse events were mild and transient. The study concludes that oxygen-enriched PRP combined with minoxidil is more effective than minoxidil alone, supporting its potential as a promising therapy for AGA.