Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations

November 2022 in “ Life ”

Afrin Yasmin, Shubhadeep Roychoudhury, Arun Paul Choudhury, A. B. Fuzayel Ahmed, Sulagna Dutta, Filomena Mottola, Vivek Verma, Jogen Chandra Kalita, Dhruv Kumar, Pallav Sengupta, Adriana Kolesárová

polycystic ovary syndrome PCOS hyperandrogenism oligomenorrhea endocrine disorder type 2 diabetes infertility

TLDR PCOS prevalence varies by ethnicity and location due to inconsistent diagnosis and limited research.

This systematic review provided an updated overview of Polycystic Ovary Syndrome (PCOS), focusing on the impacts of ethnic and geographic variations on its prevalence and clinical management. PCOS affected 8-13% of women of reproductive age and was associated with serious health risks like type 2 diabetes and infertility. The review highlighted inconsistencies in clinical symptoms based on ethnicity and geography, with indigenous women identified as high-risk populations. It emphasized the need for standardized diagnostic criteria and more research to understand PCOS's risk factors and prevalence. Management strategies included lifestyle modifications and pharmacological treatments, tailored to ethnic and regional differences. The document stressed early diagnosis and management to mitigate long-term metabolic risks.

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research Cross-Sectional Study of the Prevalence of Polycystic Ovary Syndrome in Rural and Urban Populations

11 citations , June 2019 in “International journal of gynaecology and obstetrics”

Polycystic ovary syndrome (PCOS) is more common in urban areas, possibly due to lifestyle and diet, and ignoring it can lead to serious health issues.

research Comprehensive Overview of Polycystic Ovary Syndrome

883 citations , August 2016 in “Nature Reviews Disease Primers”

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

research Polycystic Ovary Syndrome and Fertility

20 citations , January 2016 in “Open Journal of Endocrine and Metabolic Diseases”

PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.

research Prevalence of Polycystic Ovary Syndrome and Its Associated Complications in Iranian Women: A Meta-Analysis

31 citations , October 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Polycystic Ovary Syndrome (PCOS) is not very common among Iranian women, but it's important to prevent it because of the risk of heart disease and infertility.

research Clinical Characteristics of Polycystic Ovary Syndrome: Investigating Differences in White and South Asian Women

29 citations , March 2015 in “Clinical Endocrinology”

South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.

The Prevalence of Polycystic Ovary Syndrome in a Normal Population According to the Rotterdam Criteria Versus Revised Criteria Including Anti-Mullerian Hormone

research The Prevalence of Polycystic Ovary Syndrome in a Normal Population According to the Rotterdam Criteria Versus Revised Criteria Including Anti-Mullerian Hormone

221 citations , January 2014 in “Human Reproduction”

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

research Epidemiology, Diagnosis, and Management of Polycystic Ovary Syndrome

951 citations , December 2013 in “Clinical epidemiology”

PCOS is a common hormonal disorder in women that can be managed with lifestyle changes and various medications.

research Prevalence of Functional Disorders of Androgen Excess in Unselected Premenopausal Women: A Study in Blood Donors

70 citations , February 2012 in “Human Reproduction”

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

926 citations , June 2010 in “BMC Medicine”

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report

1540 citations , October 2008 in “Fertility and Sterility”

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

A Simple Screening Approach for Assessing Community Prevalence and Phenotype of Polycystic Ovary Syndrome in a Semiurban Population in Sri Lanka

research A Simple Screening Approach for Assessing Community Prevalence and Phenotype of Polycystic Ovary Syndrome in a Semiurban Population in Sri Lanka

120 citations , June 2008 in “American Journal of Epidemiology”

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

research Diagnosis of Hyperandrogenism: Clinical Criteria

85 citations , June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism”

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Health Care-Related Economic Burden of Polycystic Ovary Syndrome During the Reproductive Life Span