Polycystic Ovary Syndrome in Men

The document discusses the concept of Polycystic Ovary Syndrome (PCOS) in men, suggesting that the syndrome's manifestations are not limited to women. It references a study by Sanke et al. which found that men with early androgenetic alopecia have hormonal profiles similar to women with PCOS. The authors, Cohen and Kurzrock, had previously hypothesized nearly a decade before that male relatives of women with PCOS might also suffer from related conditions such as cardiovascular disease, diabetes mellitus, insulin resistance, and obesity. They recommended that both men and women who are first-degree relatives of patients with PCOS be evaluated for phenotypic features of PCOS and biochemical evidence of hyperinsulinemia and hyperandrogenism. The authors also suggested that treatment for the metabolic symptoms and complications associated with PCOS could be beneficial regardless of gender. The recent findings by Sanke et al. confirm the authors' hypothesis of PCOS in men.