Phosphatides in Mouse Epidermis Undergoing Normal and Abnormal Growth Changes

    April 1964 in “ PubMed ”
    C. Carruthers, A. Heining
    TLDR Phosphatide distribution in mouse skin remains consistent in both normal and cancerous growths.
    The study used silicic acid chromatography to analyze phosphatide distribution in mouse epidermis during normal hair growth and abnormal growth due to hyperplasia and carcinomas. Despite variations in total phosphatide percentages, the distribution of phosphatide classes remained consistent between normal and cancerous growths. The phosphatides identified included cardiolipin-like, phosphatidyl serine, phosphatidyl ethanolamine, inositol phosphatide, lecithin, and sphingomyelin, which were present in similar proportions across both normal and treated epidermis.
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