TLDR Oriental men may have lower androgen activity affecting hair growth despite similar testosterone levels to Caucasian men.
The study investigated the biochemical basis for differences in sexual hair growth between Oriental and Caucasian men, focusing on plasma androgen levels. Six Oriental men (3 Chinese, 3 Japanese) who could not grow facial hair were compared with six fully virile Caucasian men, all around 24 years old. Despite having similar plasma testosterone levels to Caucasians, Oriental men exhibited low 17-oxosteroid excretion and could induce beard growth with androgen, suggesting hypoandrogenism. The study aimed to explore potential differences in plasma testosterone binding or levels of other androgens.
232 citations
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June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
218 citations
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December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
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May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
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September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
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November 2018 in “Physiological Research” The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
