Platelet-Rich Plasma (PRP) for the Treatment of Androgenetic Alopecia (AGA): A Current Literature Review

April 2022 in “ Der Hautarzt ”

Paul Gressenberger, Daisy Kopera

platelet-rich plasma androgenetic alopecia PRP AGA

TLDR PRP may help with hair loss, but more research is needed.

This review from 2022 examined the use of platelet-rich plasma (PRP) injections as a treatment for androgenetic alopecia (AGA). While PRP was reported to be effective with minimal side effects, the studies reviewed were methodologically weak, making it difficult to draw definitive conclusions about its clinical efficacy. Despite this, many patients reported satisfaction with the results. The review highlighted the need for more robust, randomized controlled trials to better understand PRP's effectiveness. It also suggested that combining PRP with other treatments might enhance hair growth outcomes.

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research Evaluation of Adding Platelet-Rich Plasma to Combined Medical Therapy in Androgenetic Alopecia

5 citations , January 2021 in “Journal of Cosmetic Dermatology”

Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.

Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia

research Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia

13 citations , September 2020 in “International Journal of Molecular Sciences”

PRP therapy and minoxidil combo works best for male hair loss.

research Platelet-Rich Plasma as a Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis

15 citations , May 2020 in “Journal of Dermatological Treatment”

PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.

research Stratifying Clinical Response to Adjuvant Platelet-Rich Plasma in Patients with Androgenetic Alopecia

3 citations , April 2020 in “British Journal of Dermatology”

PRP treatment helps 70.1% of hair loss patients after two sessions.

research Platelet-Rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-Controlled Pilot Study

8 citations , January 2020 in “Acta dermato-venereologica”

PRP injections did not significantly improve hair growth.

research Treatment of Male-Pattern Alopecia with Platelet-Rich Plasma

4 citations , December 2019 in “Skin appendage disorders”

Using Platelet-Rich Plasma injections for male-pattern baldness didn't significantly improve hair growth.

research Autologous Platelet-Rich Plasma Therapy for Pattern Hair Loss: A Systematic Review

18 citations , August 2019 in “Journal of Cosmetic Dermatology”

PRP therapy may increase hair density in pattern hair loss without serious side effects, but more research is needed.

Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels

research Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels

57 citations , October 2018 in “Journal of The American Academy of Dermatology”

Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.

Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life

research Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life

19 citations , October 2017 in “The FASEB Journal”

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

research Scalp Threading with Polydioxanone Monofilament Threads: A Novel, Effective, and Safe Modality for Hair Restoration

11 citations , May 2017 in “Journal of The European Academy of Dermatology and Venereology”

Scalp threading with polydioxanone threads is a promising, effective, and safe method for hair regrowth.

research Androgenetic Alopecia: A Review

153 citations , March 2017 in “Endocrine”

Male pattern baldness involves genetics, hormones, and needs better treatments.

research Platelet-Rich Plasma by Single Spin Process in Male Pattern Androgenetic Alopecia: Is It an Effective Treatment?

27 citations , January 2017 in “Indian Dermatology Online Journal”

PRP injections can help increase hair density and thickness in men with hair loss.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

87 citations , September 2016 in “Dermatologic Surgery”

PRP shows potential for treating female hair loss, but more research needed.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations , January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study

101 citations , January 2012 in “Annals of Dermatology”

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.