Case Report: Treatment-Resistant Pityriasis Rubra Pilaris Achieving Remission with Ustekinumab

    TLDR Ustekinumab successfully treated a man's resistant skin condition when other treatments failed.
    The document from 2021 summarized various dermatological studies and case reports, with a focus on alopecia areata (AA) and its treatment challenges. It highlighted the limited success of corticosteroids and JAK inhibitors for AA due to the disease's unpredictable nature, though a systematic review suggested potential effectiveness of JAK inhibitors, warranting further evidence. The document also covered a range of other dermatological conditions and treatments, including the efficacy of tildrakizumab for psoriatic arthritis, the role of multidisciplinary clinics in managing skin cancers, and the use of AI in diagnosing melanoma. Additionally, it reported on the psychological impact of skin diseases, the need for improved dermatology training, and the potential of photo bio-modulation for treating fibrosing alopecia and nail dystrophy.
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