Additive Effects of Platelet-Rich Plasma and Systemic Therapies in Androgenetic Alopecia: A Retrospective Study

This retrospective study evaluated the effects of combining platelet-rich plasma (PRP) with systemic therapies for androgenetic alopecia (AGA) in 55 patients. The study compared hair density and width changes between PRP monotherapy and PRP combined with systemic treatments like low-dose oral minoxidil, spironolactone, finasteride, or dutasteride. Results indicated that combination therapy led to greater, though not statistically significant, improvements in hair density and width compared to monotherapy. Notably, patients with moderate AGA experienced significantly greater density improvements. The study suggests that combination therapy may be beneficial and highlights the need for further research to refine treatment strategies based on AGA severity.