Update on the Potential of Punica Granatum L. Traditional Uses and Pharmacological Uses: A Review

This review highlights the medicinal potential of <i>Punica granatum</i>, commonly known as pomegranate, which has been used traditionally to treat various diseases such as inflammation, diabetes, and cancer. The fruit peel of <i>P. granatum</i> has demonstrated multiple beneficial activities, including antioxidant, anti-inflammatory, antimicrobial, and antidiabetic effects. Both preclinical and clinical studies support its therapeutic use for ailments like menstrual pain, semen quality, knee joint arthritis, and cardiovascular diseases. However, the review emphasizes the need for more large-scale clinical trials to fully establish the effectiveness and safety profile of <i>P. granatum</i> extract for these conditions.