Preparation and In Vitro Evaluation of Protective Effects of Quercetin-Loaded Solid Lipid Nanoparticles on Human Hair Against UV-B Radiation

The study evaluated the protective effects of quercetin-loaded solid lipid nanoparticles (SLNs) on human hair against UV-B radiation. Quercetin, known for its antioxidant properties, was encapsulated in SLNs to improve its effectiveness. Various formulations were tested, and the optimal one significantly reduced hair damage, maintaining lower roughness and protein loss even after prolonged UV-B exposure. FTIR analysis confirmed that the optimized SLN formulation effectively prevented structural changes in hair proteins and lipids, suggesting its potential as an effective ingredient in hair care products to prevent sun-induced hair damage.