TLDR Topical tofacitinib helped a man with severe scalp condition after other treatments failed.
A male patient in his 50s with refractory folliculitis decalvans (FD) of the scalp, unresponsive to various treatments including antibiotics, steroids, and surgical excision, experienced significant improvement after using topical tofacitinib, a Janus Kinase inhibitor (JAKi), twice daily. After four months, his FD became clinically quiescent, and he reported complete resolution of pain and draining sinus tracts. This case highlights the potential effectiveness of topical JAK inhibitors in treating FD, a condition that is typically difficult to manage with conventional therapies.
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September 2023 in “Journal of the American Academy of Dermatology” Topical tofacitinib helped a man with severe scalp condition after other treatments failed.
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July 2019 in “Medicina Clínica (English Edition)” Tofacitinib partially improved hair regrowth in a patient with severe hair loss.
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July 2017 in “Rheumatology and Therapy” Tofacitinib, a medication for arthritis, showed potential for treating severe hair loss in a small Brazilian case series, but more research is needed.
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May 2017 in “Journal of the American Academy of Dermatology” Tofacitinib helped a 19-year-old regrow hair after other treatments failed.
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January 2017 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” A patient with complete hair loss regrew all her hair using tofacitinib.
