Regulation of Hair Follicle Cycle
January 2014
in “
PubMed
”
hair follicle cycle telogen anagen catagen follicular keratinocytes epithelial remodeling dermal remodeling sex hormones neurotrophins fibroblast growth factor transforming growth factor bone morphogenetic proteins vascular endothelial growth factor Sonic Hedgehog signaling pathways hair growth cycle growth phase resting phase regression phase keratinocyte proliferation hormones growth factors VEGF FGF TGF BMP
TLDR Hair growth is controlled by cycles influenced by hormones and various signals.
This review focused on the regulation of the hair follicle cycle, which included the phases of telogen (resting), anagen (growth), and catagen (regression). The anagen phase was marked by rapid proliferation of follicular keratinocytes, leading to hair shaft elongation and thickening. The cyclic changes involved significant remodeling of epithelial and dermal components, influenced by various factors such as sex hormones, neurotrophins, FGF, TGF, BMP, VEGF, and Sonic Hedgehog signaling pathways.
