Reversal of Alopecia Universalis by Tofacitinib: A Case Report

    November 2016 in “ Annals of Internal Medicine ”
    Morton Scheinberg, Sineida Berbert Ferreira
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    TLDR Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.
    The document from 2016 reported on the use of tofacitinib citrate, a drug approved for rheumatoid arthritis, in treating alopecia universalis. It described two cases where patients experienced progressive hair growth after prolonged administration of tofacitinib, with no adverse events noted after 9 months. Despite these positive outcomes, the authors warned of potential serious side effects from long-term use of Janus kinase inhibitors and called for clinical trials to assess the treatment's efficacy and safety for alopecia universalis. The exact number of participants was not provided.
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      in Chat  3 upvotes 10 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

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      in Treatment  2 upvotes 7 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

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      in Product  1 upvotes 7 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

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      in Treatment 3 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community 22F. Should I even bother getting a biopsy? Is there any point?

       6 upvotes 9 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

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