RNA-Seq Reveals the Roles of Long Non-Coding RNAs (lncRNAs) in Cashmere Fiber Production Performance of Cashmere Goats in China

The study investigated the roles of long non-coding RNAs (lncRNAs) in cashmere fiber production in Liaoning cashmere (LC) and Ziwuling black (ZB) goats in China, involving 12 goats in total. It identified 129 differentially expressed lncRNAs between the two breeds, with specific lncRNAs linked to fiber diameter and color regulation. The research highlighted the potential of lncRNAs in regulating cashmere fiber traits, with pathways related to fiber follicle development, cashmere fiber diameter, and color, such as the PPAR signaling pathway, metabolic pathways, and melanogenesis. The findings provided insights into the molecular mechanisms underlying cashmere fiber differences, potentially aiding in the improvement of cashmere quality through genetic and breeding strategies.