Ruxolitinib for the Treatment of Severe Alopecia Areata

    September 2018 in “ Journal of the American Academy of Dermatology ”
    Lucy Liu, Brett King
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    TLDR Ruxolitinib can help regrow hair in severe alopecia areata.
    In a study involving 8 patients with severe alopecia areata (AA), ruxolitinib, a JAK1/2 inhibitor, was shown to induce hair regrowth at a lower dose than previously reported. This finding builds on earlier research indicating the efficacy of JAK inhibitors in treating AA, highlighting ruxolitinib as a promising treatment option for severe cases.
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      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

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      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community What else is good. Besides the big 3.

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      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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