Serum Levels of IFN-γ, Complement Components C3, C4, and Vitamin D3 in the Prognosis of Patients with Alopecia Areata

March 2023 in “ 3C Empresa Investigación y pensamiento crítico ”

Teeba T. Khudair, Wala’a H. Hadi, Haneen Kadhim Zaid

alopecia areata IFN-γ interferon gamma complement component C3 complement component C4 vitamin D3 alopecia vitamin D

TLDR Alopecia areata patients have higher IFN-γ and low vitamin D3 levels.

This study investigated the role of serum IFN-γ, complement components C3 and C4, and vitamin D3 levels in the prognosis of alopecia areata (AA) by comparing 20 AA patients with 20 healthy controls. Results showed significantly elevated IFN-γ levels in AA patients (299±115.7 Pg/ml) compared to controls (73±10.84 Pg/ml), with a p-value of 0.00, indicating a strong association. While C3 and C4 levels in AA patients were within the normal range, vitamin D3 levels were found to be severely deficient (6.86±4.03). The study also noted a higher prevalence of AA among males, particularly in the 1-19 age group.

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Serum Levels of IFN-γ, Complement Components C3, C4, and Vitamin D3 in the Prognosis of Patients with Alopecia Areata

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research Serum Levels of IFN-γ, Complement Components C3, C4, and Vitamin D3 in the Prognosis of Patients with Alopecia Areata

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