Sprayable Biomimetic Double Mask With Rapid Autophasing And Hierarchical Programming For Scarless Wound Healing

    August 2024 in “ Science Advances
    Yuhe Yang, Di Suo, Tianpeng Xu, Shuai Zhao, Xiaoxiao Xu, Ho-Pan Bei, Kenneth Kak‐Yuen Wong, Qibin Li, Zijian Zheng, Bin Li, Xin Zhao
    TLDR The new sprayable wound mask helps heal wounds without scars.
    The study introduces a sprayable biomimetic double wound mask (BDM) designed for scarless wound healing, addressing the limitations of current hydrogel masks. The BDM consists of a hydrophobic top layer and a hydrophilic bottom layer, which rapidly form a bilayered structure upon application. This structure provides strong tissue adhesion and adaptiveness, with the bottom layer releasing calcium ions for quick hemostasis and the top layer maintaining a moist, sterile environment. These features work together to suppress inflammation and promote angiogenesis, offering a promising approach for scarless healing.
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