Surgical Interventions for Androgenetic Alopecia

March 2021 in “ Dermatological reviews ”

Rachel K. Lim, Carlos Gustavo Wambier, Andy Goren

androgenetic alopecia hair transplantation strip harvesting follicular unit extraction donor hair supply graft survival AGA FUE

TLDR Hair transplant works well, but needs more research for better results.

This document is a collection of articles and references discussing surgical interventions for androgenetic alopecia (AGA), the most common type of hair loss. The articles highlight the importance of having a good donor hair supply for successful hair restoration surgeries and discuss various surgical techniques, including strip harvesting and follicular unit extraction (FUE). FUE reduces visible scars, but strip harvesting results in higher graft survival. The authors note that while hair transplantation has become a successful strategy for treating hair loss, further research and innovation can improve outcomes.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

17 / 17 results

research Changing Trends in Surgical Hair Restoration: Use of Google Trends and the ISHRS Practice Census Survey

8 citations , September 2020 in “Journal of Cosmetic Dermatology”

More people are searching for hair transplants online, preferring Follicular Unit Excision over Follicular Unit Transplant. There's also a rise in female patients and interest in beard, eyebrow transplants, and non-surgical treatments like platelet rich plasma.

research Platelet-Rich Plasma Associated with Hair Transplants for the Treatment of Androgenetic Alopecia Showed No Benefits

6 citations , February 2020 in “Journal of The European Academy of Dermatology and Venereology”

No benefits found using platelet-rich plasma in hair transplants for male hair loss.

research Follicular Unit Extraction (FUE) Hair Transplant: Curves Ahead

14 citations , May 2019 in “Journal of Maxillofacial and Oral Surgery”

FUE hair transplant is a promising method with benefits like less scarring, but requires a skilled surgeon and can damage hair follicles.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version

145 citations , November 2017 in “Journal of The European Academy of Dermatology and Venereology”

Use minoxidil for hair loss treatment; assess results after 6 months.

The Effect of Plasma Rich in Growth Factors Combined with Follicular Unit Extraction Surgery for the Treatment of Hair Loss: A Pilot Study

research The Effect of Plasma Rich in Growth Factors Combined with Follicular Unit Extraction Surgery for the Treatment of Hair Loss: A Pilot Study

12 citations , October 2017 in “Journal of Cosmetic Dermatology”

Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.

research Androgenetic Alopecia: A Review

153 citations , March 2017 in “Endocrine”

Male pattern baldness involves genetics, hormones, and needs better treatments.

research Minimizing Injury to the Donor Area in Follicular Unit Extraction (FUE) Harvesting

13 citations , August 2016 in “Journal of Cosmetic Dermatology”

Using normal saline in vertical extraction for hair transplants reduces donor area injury more than acute extraction.

Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

research Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

39 citations , January 2016 in “Journal of Cutaneous and Aesthetic Surgery”

Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.

research Hair Restoration Surgery: Challenges and Solutions

31 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

research Hair Restoration Surgery: The State of the Art

32 citations , November 2012 in “Aesthetic Surgery Journal”

Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.

research Shh Maintains Dermal Papilla Identity and Hair Morphogenesis via a Noggin–Shh Regulatory Loop

138 citations , June 2012 in “Genes & Development”

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

research Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study

101 citations , January 2012 in “Annals of Dermatology”

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

research Hair Transplantation in Patients With Inadequate Head Donor Supply Using Nonhead Hair

25 citations , May 2011 in “Annals of Plastic Surgery”

Nonhead hair transplantation is effective for patients with limited head donor hair, but more research is needed.

research S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents

151 citations , August 2010 in “British Journal of Dermatology”

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

research Neural Wiskott-Aldrich Syndrome Protein Modulates Wnt Signaling and Is Required for Hair Follicle Cycling in Mice

37 citations , January 2010 in “Journal of Clinical Investigation”

N-WASP is essential for normal hair growth in mice.

research Follicular Unit Extraction: Minimally Invasive Surgery for Hair Transplantation

153 citations , August 2002 in “Dermatologic Surgery”

Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.

research Scalp Reduction Surgery for Male Pattern Baldness: Benefits, Techniques, and Complications

9 citations , July 1992 in “Clinics in Dermatology”

Scalp reduction surgery can effectively treat male pattern baldness when tailored to the patient and performed with care to minimize complications.

Related Community Posts Join

6 / 1000+ results

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 10 months ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

29 upvotes 11 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Perez Hilton Had 3 Transplants.. Yet Losing Hair.. Someone Explain?

in Transplants 71 upvotes 2 years ago

The conversation discusses Perez Hilton's hair loss despite having three hair transplants. Participants suggest that hair loss can continue after a transplant if maintenance treatments like finasteride and minoxidil are not used, and that transplanted hair can still be susceptible to loss.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Occipitalis Muscle Tension Theory

in Treatment 7 upvotes 1 week ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 73 upvotes 1 year ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

Related Research

8 / 8 results

research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss

1 citations , October 2022 in “PubMed”

Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.

research Hair Restoration

August 2021 in “Oxford University Press eBooks”

I'm sorry, but I need more information to provide a summary.

Scalp Micropigmentation as an Alternative to Hair Transplant Surgery

research Scalp Pathology for the Hair Restoration Surgeon

1 citations , November 2004 in “Hair transplant forum international”

Hair restoration surgeons must understand the differences between CTE and FPHL for accurate diagnosis and treatment.

research Biology of Scalp Hair Growth

48 citations , April 1982 in “Clinics in Plastic Surgery”